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The Facts A vitamin that dissolves in water, vitamin B12also called cobalaminplays a key role in metabolism

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Vitamin B6 (Pyridoxine) plays a role in amino acid metabolism, neurotransmitter synthesis, and immune function

That said, signs or symptoms that you may be low in vitamin B12 include: fatigue pale skin headaches symptoms of depression stomach issues difficulty focusing or concentrating pain or inflammation in the mouth or on the tongue burning or pins and needles feeling in your hands or feet muscle cramps vision changes Learn more: Signs and symptoms of B12 deficiency